The action of 5-bromouracil on.īase analogue any chemical that has a similar structure (i.e. Base analogue Any compound structurally similar to a that can substitute for a base and thus cause a mutation. Examples Aminopurine (which replaces adenine), bromouracil (which replaces thymine), azaguanine, azauracil, 5-bromodeoxyuridine. Pro b le m so lvin g.īase analogue A chemical which resembles a purine or pyrimidine base, which differs slightly in structure from the normal bases found in nucleic acids (DNA or RNA) and, when intercalated in the nucleic acid, may alter one or more of its normal functions or cause point (single-base substitution) mutations. M ath e matical critical an alysis – h e u ristic. Table 2.1 The Four Resources Model (FRM) according to Freebody and Luke (2003) and.
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